GOING ABOVE AND BEYOND

In vitro ADME/Tox

We perform in vitro absorption, distribution, metabolism, and excretion (ADME) assays for compound screening and lead selection/optimization in drug discovery, IND enabling studies in preclinical evaluation, as well as studies to support clinical development.

--   We are accomplished scientists from large and small pharmaceutical, biotech, and CRO companies.

--   We consistently provide high-quality work at a low cost.

--   We offer free consultations on study design, data interpretation, and structure optimization.

--   We have new customer, volume, and loyalty discount programs.

--   We go above and beyond to exceed our customers' expectations.

--   We are located in the U.S. and will provide the best customer experience.

​​BioANALYSIS

We measure concentrations of parent compound / metabolites in biological fluids and tissues using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to support drug discovery, preclinical evaluation, and clinical development.

Why US?


ADME   PK   Bioanalysis   Formulation

​Services and Consultation

Formulation

We develop formulations for drug discovery PK, preclinical toxicology and clinical development. Formulations include solutions, suspensions, microemulsions, and capsules. Formulation selection is based on stability, safety and ADME/PK properties.

In vivo PK

We conduct standard in vivo pharmacokinetic (PK) studies and dose linearity PK evaluations for discovery compounds. We also perform salt or formulation screening PK and food-drug interaction PK for lead selection and general toxicology studies.

Consultation

We offer consultation on ADME/PK study design, data interpretation, structure-property relationship, and lead selection/optimization strategies. Consultation is complimentary when the study is conducted at Touchstone Biosciences.